Treatment of Cushing's Disease if Surgery Fails
"Bilateral adrenalectomy is usually reserved and employed as a last resort when all else has failed and the patient is in grave danger due to the consequences of high cortisol levels. However, the success and relatively low risk of complications of laparoscopic bilateral adrenalectomy prompts us to reconsider our attitudes towards adrenalectomy in patients with residual and recurrent Cushing's disease. Perhaps adrenalectomy should be employed earlier in the course of treatment of patients with refractory Cushing's disease."
Guidelines for Doctors and their Patients who have Residual Cushing's Disease
Lewis S. Blevins, Jr. MD and Gwen Stanhope, PA-C
California Center for Pituitary Disorders at University of California, San Francisco